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He washospitalized because of his elevated liver enzymes & creatininekinase, abdominal pain and diarrhea which was diagnosed to be anADR’s from colchicine overdose. Antral gastritis and alkaline refluxwas diagnosed on esophagogastroduodenoscopy along with minimalintestinal wall edema in the left abdomen. He was started onmeropenem 3×1 which was later changed to cefepime 3×1 and 3×10 mg/kgacyclovir was also added to treatment as a possible differentialdiagnosis for herpetic and opportunistic encephalitis . The patient alsohad complaint of headache (occipital and bilateral frontal regions),blurred vision, nausea, vomitingand speech impairment during the follow up period. After a dayfollowed by his symptoms he had generalized seizures for which hisneurologist prescribed him oxcarbazepine 2×150 mg.

He also vomittedan ascaris lumbricoides the same day for which he was treated withmebendazole 3×100 mg for 3 days. His brain CT scan showedintracerebral hematoma or opportunistic infection in the rightoccipital lobe. Later his brain MRI was done in which PRES wasdiagnosed. Mycophenolate mofetil was withdrawn and everolimus 2×0.75mg was continued as to prevent the ADRs from the previous drug.

Hisblood pressure was strictly monitored with amlodopin 1×10 mg.Oxcarbazepine was stopped 2 months later and the patient had recoverdfrom his post kidney transplant ADRs.