Abstract pain, no hematuria, no dysuria, no urgency and

AbstractChondroma is a benign tumour of mesenchymal origin and slow growththat is composed of cartilage, Extra-skeletal presentation of chondromas isextremely rare and mostly occurs in the soft tissues of the extremities, mainlyin the hands and feet (1, 2 and 3). Bladder chonrdoma is very rare condition and only five cases had beenreport up to date. Introduction Chondromais a benign tumour of mesenchymal origin and slow growth that is composed ofcartilage, Extra-skeletal presentation of chondromas is extremely rare andmostly occurs in the soft tissues of the extremities, mainly in the hands and feet(1, 2 and 3).  Bladder chonrdoma is veryrare condition and only five cases had been report up to date.

Soft tissue chondromas usually affect both sexes equally, between40 and 70 years of age (5). The origin of this type of tumour is not clear;however, Huggins (1931) described the ability of the urothelium to induce boneand cartilaginous metaplasia (6). A 50-year- old female patient presented with nonspecificsuprapubic pain and bilateral loin pain, on Cystoscopy found  small projection from anterior wall of thebladder with intact urothelium, looks like from outside. Managed bytransurethral resection. It is necessary to accumulate more cases to obtainadequate conclusions and to better understand the causes of this pathology.  Case report A 50-year- old female patient presented with nonspecificsuprapubic pain and bilateral loin pain, no hematuria, no dysuria, no urgencyand frequency.

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She is a known case of DM. and appendectomy done before.She is not smoker and house wife. On ultrasound examination she had  Rt.

Lateral growth about 12*10 mm.Cystoscopy had done for her, found grade 2 bladder trabeculationand small projection from anterior wall of the bladder with intact urothelium,looks like from outside.  Transurethral resection donefor her, there was whitish friable tissue with avascular core Gross examination of tissue:  two sections,first one Single gray white fragment of tissue 5 mm in diameter, and secondone two tiny gray white fragments of tissue 8 mm in aggregate.

all takenMicroscopically first one section of this part of biopsy showsthick bundles of detrusor muscle of urinary bladder bordered by submucosal softtissue on one side and by edge of chondroid lesion on the other side, and thesecond one the section show the outlines of lobulated nodule that has Centre ofhyalined cartilage with scattered chondrocyte and an outer rim of partiallyossified lamellar bone with few osteocytes. There is no evidence of granulomadysplasia or invasive malignancy. Discussion Soft tissue chondroma is benign nodules of hyaline cartilage thatis not attached to bone and tend to occur in hand and feet. Rare occurrence hasbeen reported in various pelvic organs, including the prostate, bladder, scrotum,and testis.

(4) Soft tissue chondromas usually affect both sexes equally, between40 and 70 years of age (5). The origin of this type of tumour is not clear;however, Huggins (1931) described the ability of the urothelium to induce boneand cartilaginous metaplasia (6). The most common mesenchymal tumours of the bladder are leiomyomas, leiomyosarcomas, and pleomorphicundifferentiated sarcomas (formerly malignant fibrous histiocytoma).(7)There are a number of similarities between this and previouscases, all six cases were in women between the ages of 50-75 year, and allarise from anterior wall of the bladder. The similarities in the ages of thewomen and the consistent anterior location of their tumors were interesting;however, no conclusions can be drawn from such a small sample size.

Some studies seem to correlate the pathogenesis of this tumourwith the possible genetic influence demonstrated in monosomies, trisomies,translocations, and rearrangement of trisomy 11 in cytogenetic studies of softtissue chondromas (8) however; clonal mutation has not yet been demonstrated(9).Because of its rarity, there is no standard management. Allreported cases were managed primarily with transurethral resection andcystoscopic surveillance. Complete resection is considered curative (10),although because of reported local recurrence rates of 15-20% (10) and lack ofspontaneous regression (11), ongoing surveillance is recommended  Conclusion Soft tissue chondroma of the bladder is a benign subepithelialtumour that has rarely been reported, possibly due to under recognition andunder diagnosis.  It is necessary toaccumulate more cases to obtain adequate conclusions and to better understandthe causes of this patholog