Introduction: Depression is one of the commonest psychiatric disorder in today’s
era worldwide. According to the National Institute of Mental Health, major
depressive disorder is characterized by a combination of symptoms that
interfere with a person’s ability to work, sleep, study, eat, and enjoy
once-pleasurable activities. Depression is not directly described in Ayurvedic
texts but similar conditions named “Avasada” and “Vishada” are observed.  The synthetic antidepressant drugs are proved
to be of a great benefit in this illness, but have many limitations besides
their serious side effects including the problem of addiction and drug abuse. Hence
there is a need to discover indigenous drugs for this condition, which are proved
less harmful.

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Aims & objective: To collect information of various
Medicinal herbs proven Anti Depressive.

Material & Methods: In the present study various
articles, Journals and Textbooks concern of Medicinal herbs in Depression are scrutinized.

Observations & Results: The present study reveals that
there are various Medicinal Herbs which are proven as anti depressant with help
of experimental and clinical studies. Medicinal Herbs like Ashvagandha (Withania somnifera), Kapikachhu (Mucuna pruriens),
Vacha (Acorus calamus), Nagarmotha (Cyperus rotundus), Hypericum mysoresne
– Folklore plant, Tamalpatra (Cinnamomum tamala), Yastimadhu (Glycyrrhiza
glabra), Maricha (Piper nigrum), Bibhitaki (Terminalia bellerica), Kaidarya (Murraya
Koienegi), Bramhi (Bacopa monniera), Jyotishmati
(Celastrus paniculatus), Vishnukrantha
(Evolvulus alsinoides), Sahadevi (Vernonia cineria) etc. are found to be evaluated for  anti depressive action. In
this context of various herbal drugs appear to be of potential value in the
treatment of depression.

Various Medicinal herbs are observed having antidepressant activity and can be
used in Depression to overcome the side effects of synthetic antidepressant drugs.

Keywords: Depression, anti depressant activity, Avasada, Visada